Poly (lactic-co-glycolic acid) (PLGA) porous scaffold for tissue engineering. Enlargement of a Pore. Average Pore Size 350-550 mm, porosity estimated at 35-45%
Image by CORE-Materials
DoITPoMS, University of Cambridge
The patients own cells are seeded onto the scaffold and allowed to attach and start producing new bone. The construct is implanted into the defect site, where eventually the polymer will biodegrade and be completely removed, leaving a natural autogenous bone graft. This technique is particularly useful for large defects, or where the host bed is compromised due to disease, although it is still at the research stage.
System
Poly (lactic-co-glycolic acid) (PLGA)
Composition
Not specified
Reaction
Processing
PLGA melt cast, particulate leaching (NaCl)
Applications
Tissue Engineering Scaffold for Bone Cells (Osteons) or Cartilage (Chondrocytes)
Sample preparation
Freeze fractured using liquid nitrogen, gold sputter coated
Technique
Scanning electron microscopy (SEM)
Contributor
V A Mellon
Organisation
Department of Materials Science and Metallurgy, University of Cambridge
View micrograph in DoITPoMS website
Naturhistorisches Museum Detail - Helios
Image by flo_p
Detail of the Vienna Natural History Museum's (NHM) cupola. The statue (of the greek sun god Helios) is naked, signifying science's quest to uncover everything in nature. Opposite the NHM is the Art History Museum, which looks highly similar. The statue above its cupola, however, is clothed.
This is a scan from an enlargement, not from the negative. It is therefore of lower quality.
dewdrop falls down in 1 sec...
Image by gertschi911
EOS 400D + MPE 65 / natural light / enlargement factor 1
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